6th International Caparica Conference in SPLICING 2025

20th – 24th July 2025 | Caparica | Portugal

Oral Speakers

Tal Shay, PhD

Ben-Gurion University of the Negev (Israel)

Identify Transcriptional and Splicing Signatures along the Suppression-Activation trajectory of Natural Killer Cells

Zhiming Li, PhD

Huazhong University of Science and Technology (China)

FBXO24 is essential for male fertility and spermiogenesis by regulating alternative splicing

Kristoffer Vitting-Seerup, PhD

The Technical Univeristy of Denmark (DTU), Department of Health Technology (Denmark)

Harvesting the Unused Potential of Molecular Biology: The Importance of Analyzing Isoforms

Kathy Magnusson, PhD

Oregon State University (USA)

Altered synaptic localization of C-terminal splice variants of the GluN1 subunit of the NMDA receptor in the hippocampus of old mice with impaired spatial memory.

Laurent Corcos, PhD

INSERM U78 – Université de Brest (France)

Recognition of 3’ splice sites in microsatellite instable cancers

Uwe Wolfrum, PhD

Johannes Gutenberg University Mainz; Institute of Molecular Physiology; Molecular Cell Biology (Germany)

The Usher syndrome 1G protein SANS ensures correct pre-mRNA splicing of retinal transcripts

Mercedes Prudencio, PhD

Mayo Clinic (USA)

Cryptic RNA and proteins as biomarkers of TDP-43 dysfunction for TDP-43 proteinopathies

Delphine Bouvet, PhD

Sorbonne Université, Pitié-Salpêtrière Hospital (France)

Studying the impact of genomic variants on mRNA splicing in the context of routine molecular diagnostic of rare genetic diseases

Kazuyuki Matsushita, PhD

Chiba University (Japan)

The Link of mRNA and rRNA Transcription by PUF60/FIR through TFIIH/P62 as a Novel Therapeutic Target for Cancer

Erzsébet Fekete, PhD

University of Debrecen (Hungary)

The Presence of a Near-Terminal Fully-Complementary Double-Stranded RNA Element is Associated with Near-Identical [D1,2] Stwintrons Located in Different, Unlinked Genes

Laurence Arbibe, PhD

Institut Necker Enfants Malades (France)

A Non-Canonical RNA Splicing Signature uncovers Aging Marks in Inflammatory Bowel Disease

Hadas Ner-Gaon, PhD

Ben-Gurion University of the Negev (Israel)

Comparing the use of alternative splicing between human and mouse immune cells

Yusuke Suenaga, PhD

Laboratory of Evolutionary Oncology, Chiba Cancer Center Research Institute (Japan)

Global changes in open reading frame dominance of RNAs during cancer evolution

Liang Wang, PhD

Moffitt Cancer Center (USA)

Genetic and Epigenetic Roles in Regulating Gene Splicing Changes at Prostate Cancer Risk Loci

Delphine Bernard, PhD

Brest University (France)

de novo variants in the splicing factor gene SF3B1 are associated with neurodevelopmental disorders

Daria A. Gaykalova, PhD

University of Maryland, Ba (USA)

Head and Neck Squamous Cell Carcinoma: Alternative Splicing Events as Oncogenic Drivers and Potential Therapeutic Targets

Peter Sparber, PhD

Research Centre for Medical Genetics (Russia)

Comprehensive Analysis of 100+ Exonic and Intronic Splicing Variants in the SCN1A Gene Using 21 Minigene Constructs

Jeanmarie Verchot, PhD

Texas A&M University (USA)

Changing the Accumulation of Transcript isoforms and Genes Involved in RNA Metabolism are Seen in Plants Subjected to ER Stress and Plant Virus Infection

Ping Liao, PhD

National Neuroscience Institute (Singapore)

Impact of alternative splicing of CaV1.2 channel on cardiovascular physiology, pharmacology, and pathophysiology

Leena Ibrahim, PhD

King Abdullah University of Science and Technology (Saudi Arabia)

Role of Alternative Splicing in Neuronal Development and Circuit Integration

Marcel Köhn, PhD

University of Halle-Wittenberg (Germany)

Alternative splicing control of focal adhesion genes by RBFOX1 in cardiac muscle cells

Alice Wedler, PhD

Martin Luther University Halle-Wittenberg (Germany)

Alternative Splicing by RAVER1: A New Level of Signaling Regulation

Nishanth M J, PhD

St Joseph’s University (India)

Functional conservation and diversification of hnRNP interactomes in eukaryotes

David Rekosh, PhD

University of Virginia (USA)

The HERV-K Rec RNA Export Protein Can Act as a Tumor Promoter in Conjunction with a Mutant H-Ras Protein

Marie-Louise Hammarskjold, PhD

University of Virginia (USA)

BUD13 Regulates Nuclear Retention of Cellular and HIV RNAs with Retained Introns

Chien-Yu Huang, PhD

Louisiana State University AgCenter (USA)

Chromatin remodelers modulate plant NLRs expression directly and indirectly via alternative splicing

Liliana Florea, PhD

Johns Hopkins University (USA)

The Long and Short of It: Differential Splicing Detection from RNA Sequences with MntJULiP

Raul Mateos, PhD

National Cancer Center Research Institute (Japan)

Splicing Junction-based Classifier for Detecting Abnormal KEAP1-NRF2 System Activation

Kai Erdmann, PhD

University of Sheffield (UK)

A role of the splicing factor PTBP1 in mechanotransduction

Mathieu Quesnel-Vallières, PhD

Université de Sherbrooke (Canada)

Discovery of tissue-specific alternative splicing in human

Johannes Ptok, PhD

University Hospital Düsseldorf (Germany)

Fully haplotyped genome assemblies of healthy individuals reveal variability in 5’ss strength and support by splicing regulatory proteins

Jean-Philippe Brosseau, PhD

Université de Sherbrooke (Canada)

Regulation of cancer-associated alternative splicing programs by extra cellular factors

Akshay Bhinge, PhD

University of Exeter (UK)

Dysregulation of RNA processing as a driver of neuronal dysfunction in ALS

Eric Batsche, PhD

CNRS (France)

Antisense transcription directly influences the regulation of alternative splicing

Maria Cristina Carlan da Silva, PhD

Universidade Federal do ABC (Brazil)

Human Cytomegalovirus UL111A spliced transcripts and protein isoforms

Olivier Saulnier, PhD

Institut Curie (France)

Medulloblastoma’s developmental origins: how does alternative splicing drive subgroup-specific tumorigenesis?

Shipra Agrawal, PhD

Stony Brook University (USA)

Alternative Splicing and Regulation of the Glomerular Filtration Barrier in Kidney Disease

Iris Chiara Salaroglio, PhD

University of Turin (Italy)

Breaking Cancer Resistance: Targeting the ROS/HIF-1α/C/EBP-β Axis in Hypoxic Non Small Cell Lung Cancer

Olivier Pardo, PhD

Imperial College London (UK)

Leo Qian, PhD

Entrada Therapeutics (USA)

Gustavo Bressan, PhD

Federal University of Viçosa (Brazil)

Novel Insights into the Oncogenic Role of Serine/Arginine Protein Kinase 2 (SRPK2) in Melanoma

Oxana Ryzhkova, PhD

Research Centre for Medical Genetics (Russia)

Valeriia Kovalskaia, PhD

Research Centre for Medical Genetics (Russia)

Victoria Shender, PhD

Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine (Russia)

Michal Kramárek, PhD

Masaryk University, Brno (Czech Republic)

Valer Gotea, PhD

National Human Genome Research Institute (NHGRI / NIH) (USA)

Mousumi Mutsuddi, PhD

Banaras Hindu University (India)

Role of Impaired Splicing in Health and Disease